Neurotoxin injections are among the most requested aesthetic treatments in the world. Known for their ability to smooth wrinkles, prevent new lines from forming, and even slim certain facial or body areas, neurotoxins have become a trusted tool for people who want to refresh their appearance without surgery. They are also used for a variety of therapeutic purposes, from easing jaw clenching to reducing excessive sweating.
When considering this treatment, many people wonder which neurotoxins are available and how they differ. The three most widely used options are Botox, Dysport, and Xeomin. Each works in a similar way by relaxing targeted muscles, yet subtle differences can make one a better choice depending on your goals and anatomy.
This blog explores how neurotoxins work, what sets Botox, Dysport, and Xeomin apart, and what to expect from treatment. By the end, you’ll have a clear understanding of the options so you can discuss the best choice with your provider.
Understanding Neurotoxins
Neurotoxins used in cosmetic medicine are purified proteins derived from Clostridium botulinum. While the word “toxin” may sound intimidating, these injectables have been extensively studied, refined, and safely used in both medical and cosmetic settings for decades.
Their mechanism is straightforward: they block nerve signals to targeted muscles, preventing those muscles from contracting as strongly. When the muscles relax, the skin above them also smooths out, reducing the appearance of lines and wrinkles. Over time, neurotoxin treatments can also prevent new wrinkles from forming because repeated contractions are minimized.
Beyond aesthetics, neurotoxins are FDA-approved and widely used to treat conditions such as:
- Chronic migraines
- TMJ-related jaw pain
- Excessive underarm sweating (hyperhidrosis)
- Muscle spasms in the neck, eyelids, or limbs
Their versatility, safety record, and proven effectiveness make them one of the most trusted nonsurgical treatments in modern aesthetics.
Botox
Botox is the most recognized neurotoxin brand and was the first to be approved for cosmetic use. Because of its long history, it is often the product people think of when they hear “neurotoxin.”
How Botox Works
Like other neurotoxins, Botox temporarily blocks the communication between nerves and muscles. The effect is a reduction in muscle activity, which softens the lines created by repeated facial expressions.
Common Treatment Areas
- Forehead lines
- Frown lines between the eyebrows (often called “11 lines”)
- Crow’s feet around the eyes
- Bunny lines on the nose
- Neck bands
- Jaw clenching and TMJ-related discomfort
Longevity and Results
Most clients begin noticing improvements within 3–5 days of treatment, with full results visible around two weeks. The effects typically last about 3–4 months, though some individuals see results for up to 6 months, depending on their metabolism and treatment area.
Unique Benefits of Botox
- The most studied and widely used neurotoxin worldwide
- Versatile, with a broad range of cosmetic and therapeutic uses
- Predictable results when administered by trained professionals
Who Is Botox Best For?
Botox is an excellent choice for anyone looking for reliable, time-tested results. If you want smoother skin and proven treatment for lines and wrinkles, Botox is often the go-to option.
Dysport
Dysport is another FDA-approved neurotoxin that has become increasingly popular. While it works in much the same way as Botox, there are small differences that may make it better suited for certain clients.
How Dysport Works
Dysport spreads a little more easily under the skin than Botox. This characteristic makes it particularly effective for treating larger areas, such as the forehead, where even distribution is important for natural-looking results.
Common Treatment Areas
- Forehead lines
- Frown lines between the eyebrows
- Crow’s feet
- Jawline contouring
- Excessive sweating (hyperhidrosis)
Longevity and Results
Dysport often works slightly faster than Botox. Many clients notice changes in as little as 2–3 days, compared to the 3–5 days typical for Botox. Results last about 3–5 months, depending on individual factors.
Unique Benefits of Dysport
- Faster onset than Botox for many clients
- Effective for larger treatment areas due to its spreadability
- Provides smooth, even results when used on broad muscles
Who Is Dysport Best For?
Dysport is often recommended for clients seeking faster results or those looking to treat wider areas such as the forehead. It is also an excellent choice for people who metabolize neurotoxins quickly and want a slightly longer duration between touch-ups.
Xeomin
Xeomin is the third major neurotoxin available and is sometimes referred to as the “naked” neurotoxin. Unlike Botox or Dysport, Xeomin does not contain accessory proteins, which gives it some unique advantages.
How Xeomin Works
Xeomin works in the same way as Botox and Dysport by temporarily relaxing targeted muscles. However, because it does not include additional proteins, it is considered a purer formulation.
Common Treatment Areas
- Frown lines between the eyebrows
- Forehead wrinkles
- Crow’s feet
- TMJ-related jaw clenching
Longevity and Results
Xeomin usually takes about 4–5 days to show results, similar to Botox, and effects last around 3–4 months.
Unique Benefits of Xeomin
- “Naked” formulation reduces the risk of resistance (antibodies forming against the treatment)
- Often preferred for clients who have stopped responding to Botox or Dysport
- Provides natural-looking results with consistent safety
Who Is Xeomin Best For?
Xeomin is a strong option for clients who want a clean, additive-free neurotoxin or who have built up resistance to other products. It is also ideal for individuals who prefer a minimalist formulation.
Comparing Botox, Dysport, and Xeomin
While all three neurotoxins work similarly, there are subtle differences:
| Botox | Dysport | Xeomin | |
| Onset | 3–5 days | 2–3 days | 4–5 days |
| Duration | 3–4 months (sometimes 6) | 3–5 months | 3–4 months |
| Spread | Moderate | Wider spread (good for large areas) | Targeted, precise |
| Unique Feature | Most researched, versatile | Faster onset, good for broad areas | “Naked” formulation, reduced risk of resistance |
The best choice depends on your goals, anatomy, and preferences. All three are safe and effective when administered by a qualified injector.
The Treatment Process
Neurotoxin treatments follow a straightforward process designed to maximize both comfort and results.
Consultation
Your provider will begin with a consultation to understand your goals, medical history, and areas of concern. They will recommend the best neurotoxin option for you.
Treatment Session
The procedure is quick, often taking only 15–30 minutes. After cleansing the treatment area, the provider will use a fine needle to inject small amounts of neurotoxin into targeted muscles. A numbing cream may be used for added comfort, though most clients describe the injections as just a quick pinch.
Aftercare
- Avoid rubbing the treated area for several hours.
- Remain upright for about 4 hours.
- Skip strenuous workouts for 24 hours.
Recovery and Downtime
There is little to no downtime. Most people resume their daily activities right away, with only minor redness or swelling that fades quickly.
Results and Expectations
Onset: Dysport may show results in 2–3 days, Botox in 3–5 days, and Xeomin in 4–5 days.
Peak results: About 1–2 weeks after treatment.
Duration: Results typically last 3–5 months. Consistent treatments can extend longevity and help “train” facial muscles to contract less forcefully over time.
Outcome: Natural-looking rejuvenation, smoother skin, and prevention of new wrinkles when performed by skilled injectors.
Final Thoughts
Botox, Dysport, and Xeomin are the three leading neurotoxins in aesthetic medicine. While they all work by relaxing targeted muscles to smooth and prevent wrinkles, each has unique qualities that may make it more suitable for certain goals or preferences. Botox is the most established and versatile, Dysport often works faster and spreads more evenly across larger areas, and Xeomin offers a pure formulation that reduces the risk of resistance.
The best way to determine which neurotoxin is right for you is through a consultation with an experienced provider. With professional guidance, you can achieve refreshed, natural-looking results that enhance your confidence.
FAQs About Neurotoxins
What are neurotoxins used for?
They are primarily used to smooth wrinkles and fine lines, but they can also treat jaw clenching, migraines, excessive sweating, and muscle spasms.
How long do neurotoxin results last?
Results generally last 3–5 months, depending on the product, your metabolism, and the treatment area.
Does the injection process hurt?
Most clients describe the feeling as a small pinch. A numbing cream can be applied to make the experience more comfortable.
How quickly will I see results?
Dysport often works in 2–3 days, Botox in 3–5 days, and Xeomin in 4–5 days. Full results appear after about two weeks.
Can neurotoxins prevent wrinkles from forming?
Yes. By relaxing the muscles responsible for repeated expressions, neurotoxins can prevent the development of deeper wrinkles over time.
What’s the difference between Botox, Dysport, and Xeomin?
All work similarly, but Botox is the most studied, Dysport spreads more easily and may act faster, and Xeomin is a pure formulation without accessory proteins.
Are there any side effects?
Mild redness, swelling, or bruising at the injection site may occur, but these typically resolve within a few days. Serious side effects are rare when injections are performed by a qualified professional.
Who is a good candidate for neurotoxin treatments?
Most healthy adults seeking smoother skin or relief from conditions like TMJ or hyperhidrosis are good candidates. Pregnant or breastfeeding individuals should avoid treatment.
Can neurotoxin treatments look natural?
Absolutely. When performed by skilled injectors, neurotoxin treatments enhance your appearance without creating a “frozen” look.
How often should I schedule treatments?
Most clients book treatments every 3–4 months to maintain consistent results.
